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Article

Genetic variants of mannose-binding lectin 2 gene influence progression and prognosis of patients with hepatitis B virus infection in China.

Clinics and research in hepatology and gastroenterology - 1 Nov 2016

Gu Xing, Ji Qiang, Wang Hao, Jiang Mingming, Yang Juan, Fang Meng, Wang Mengmeng, Gao Chunfang

Abstract excerpt

AIM: Mannose-binding lectin (MBL) is a member of the calcium-dependent collectin family involved in the innate immune system that mediates phagocytosis and activates complement by binding to carbohydrate motifs. We studied allele and haplotype frequencies of -221C/G and codon 54G/A in MBL2 gene to reveal their relationship with the developing and progression of hepatitis B virus (HBV)-related liver diseases....

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Source

Identifiers

PMID: 26857650
DOI: 10.1016/j.clinre.2015.12.015

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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