Article
Association of hepatitis C virus infection and liver fibrosis severity with the variants alleles of MBL2 gene in a Brazilian population.
Human immunology - 1 Sept 2010
Halla Maria Cristina, do Carmo Rodrigo Feliciano, Silva Vasconcelos Luydson Richardson, Pereira Luciano Beltrão, Moura Patricia, de Siqueira Erika Rabelo Forte, Pereira Leila Maria Moreira Beltrão, Mendonça Cavalcanti Maria do Socorro de
Abstract excerpt
Mannose binding lectin (MBL) is a molecule of the innate immunity, which activates the complement system and modulates inflammation. We investigated the association of the polymorphisms in the exon 1 and promoter region of the MBL gene (MBL2) with the susceptibility to hepatitis C virus (HCV) infection and the degree of liver fibrosis in Brazilian patients chronically infected with HCV. The study was performed in...
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