Article
Effects of MASP2 haplotypes and MASP-2 levels in hepatitis C-infected patients.
International journal of immunogenetics - 1 Jun 2018
Silva Amanda A, Catarino Sandra J, Boldt Angelica B W, Pedroso Maria Lucia A, Beltrame Marcia H, Messias-Reason Iara J
Abstract excerpt
Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) are components of the lectin pathway, which activate the complement system after binding to the HCV structural proteins E1 and E2. We haplotyped 11 MASP2 polymorphisms in 103 HCV patients and 205 controls and measured MASP-2 levels in 67 HCV patients and 77 controls to better understand the role of MASP-2 in hepatitis C susceptibility and...
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