Article
Association study between mannose-binding lectin haplotypes and X gene mutation of hepatitis B virus from treatment naïve patients.
Aging - 7 Nov 2016
Su Chenghao, Lin Yong, Mao Qianguo, Wu Daitze, Zhu Lina, Najera Isabel, Garcia-Alcalde Fernando, Niu Jianjun
Abstract excerpt
Mannose binding lectin (MBL) plays important role in the innate immunity of human. Mutations in the MBL2 gene can significantly change the serum level of MBL, and consequently alter the susceptibility and progression of infectious disease. However, the association between the MBL2 profile and the HBV mutation and quasispecies complexity has not yet been reported. Our approach includes the study of the MBL2 gene...
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