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Article

Mannan-binding lectin MBL2 gene polymorphism in chronic hepatitis C: association with the severity of liver fibrosis and response to interferon therapy.

Clinical and experimental immunology - 1 May 2008

Alves Pedroso M L, Boldt A B W, Pereira-Ferrari L, Steffensen R, Strauss E, Jensenius J C, Ioshii S O, Messias-Reason I

Abstract excerpt

Hepatitis C virus (HCV) is a major cause of hepatic disease and of liver transplantation worldwide. Mannan-binding lectin (MBL), encoded by the MBL2 gene, can have an important role as an opsonin and complement activating molecule in HCV persistence and liver injury. We assessed the MBL2 polymorp...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Cirrhosis

Share to Mannose-Binding Lectin

Share to Polymorphism, Single Nucleotide

Share to Severity of Illness Index

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Source

Open in PubMed Open full text

Identifiers

PMID: 18336595
DOI: 10.1111/j.1365-2249.2008.03614.x
PMCID: PMC2384100

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18336595-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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