Article
Mannose-binding lectin MBL2 gene polymorphisms and outcome of hepatitis C virus-infected patients.
Journal of clinical immunology - 1 Sept 2008
Koutsounaki Eirini, Goulielmos George N, Koulentaki Mary, Choulaki Christianna, Kouroumalis Elias, Galanakis Emmanouil
Abstract excerpt
INTRODUCTION: Mannose-binding lectin (MBL) is involved in host's response to several infections including hepatitis B but little is known about MBL and hepatitis C virus (HCV) infection. The present study attempts to investigate whether MBL2 genotype and serum MBL levels affect the course of HCV infection. RESULTS AND DISCUSSIONS: We investigated the variant alleles in MBL2 gene promoter and exon-1 regions in 80...
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