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Article

MASP2 gene polymorphism is associated with susceptibility to hepatitis C virus infection.

Human immunology - 1 Oct 2011

Tulio Siumara, Faucz Fabio R, Werneck Renata I, Olandoski Márcia, Alexandre Rodrigo B, Boldt Angélica B W, Pedroso Maria Lucia, de Messias-Reason Iara J

Abstract excerpt

Hepatitis C virus (HCV) has become a major public health issue and is prevalent in most countries. We examined several MASP2 functional polymorphisms in 104 Brazilian patients with moderate and severe chronic hepatitis C using the primers set to amplify the region encoding the first domain (CUB1), a critical region for the formation of functional mannan-binding lectin (MBL)/MBL-associated serine proteases...

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Identifiers

PMID: 21843573
DOI: 10.1016/j.humimm.2011.06.016
PMCID: PMC7115369

Genes

MASP2

Variants

Provenance

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