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Article

Mammalian Alternative Translation Initiation Is Mostly Nonadaptive.

Molecular biology and evolution - 1 Jul 2020

Xu Chuan, Zhang Jianzhi

Abstract excerpt

Alternative translation initiation (ATLI) refers to the existence of multiple translation initiation sites per gene and is a widespread phenomenon in eukaryotes. ATLI is commonly assumed to be advantageous through creating proteome diversity or regulating protein synthesis. We here propose an alternative hypothesis that ATLI arises primarily from nonadaptive initiation errors presumably due to the limited ability...

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Identifiers

PMID: 32145028
DOI: 10.1093/molbev/msaa063
PMCID: PMC7828576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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