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Article

Functional characterization of 5’ UTR <i>cis</i> -acting sequence elements that modulate translational efficiency in <i>P. falciparum</i> and humans

2021-09-07

Abstract excerpt

<h4>Background</h4> The eukaryotic parasite Plasmodium falciparum causes millions of malarial infections annually while drug resistance to common antimalarials is further confounding eradication efforts. Translation is an attractive therapeutic target that will benefit from a deeper mechanistic understanding. As the rate limiting step of translation, initiation is a primary driver of translational efficiency. It...

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Literature Corpus work
2f33aff6-1acb-5a84-beee-82e652901d02
DOI
10.1101/2021.09.07.459299
Open publication

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Functional characterization of 5’ UTR <i>cis</i> -acting sequence elements that modulate translational efficiency in <i>P. falciparum</i> and humansDOI 10.1101/2021.09.07.459299
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