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Article

<i>In situ</i> administration of cytokine combinations induces tumor regression

2018-02-05

Abstract excerpt

Recent advances in cancer immunotherapy suggest a possibility of harnessing the immune system to defeat malignant tumors, but complex immunosuppressive microenvironment confined the therapeutic benefits to a minority of patients with solid tumors. Here we constructed a lentivector based inducible system to evaluate the therapeutic effect of cytokines in established tumors. Doxycycline (Dox) induced local expressio...

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Literature Corpus work
380a5a5b-04a8-5cf1-9d45-71d5429e0277
DOI
10.1101/260547
Open publication

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<i>In situ</i> administration of cytokine combinations induces tumor regressionDOI 10.1101/260547
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