Article

Turning anecdotal irradiation-induced anti-cancer immune responses into reproducible in situ cancer vaccines via disulfiram/copper-mediated enhanced immunogenic cell death of breast cancer cells

2023-08-18

Abstract excerpt

<title>Abstract</title> <p>Irradiation (IR) induces immunogenic cell death (ICD) in tumors, but it rarely leads to the abscopal effect (AE). However, combining IR with immune checkpoint inhibitors has shown anecdotal success in inducing AEs. In this study, we aimed to enhance the IR-induced immune response and generate reproducible AEs using the anti-alcoholism drug disulfiram (DSF) and copper complex (DSF/Cu) vi...

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Literature Corpus work: 675985ba-4cde-5498-8e4b-cbc6a01aec26
DOI: 10.21203/rs.3.rs-3195392/v1

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Turning anecdotal irradiation-induced anti-cancer immune responses into reproducible in situ cancer vaccines via disulfiram/copper-mediated enhanced immunogenic cell death of breast cancer cellsDOI 10.21203/rs.3.rs-3195392/v1Read

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