Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of chitosan co-formulation in enhancing interleukin-12 delivery and antitumor activity.

Biomaterials - 1 May 2013

Yang Lirong, Zaharoff David A

Abstract excerpt

Local delivery systems that provide sustained, high concentrations of antitumor cytokines in the tumor microenvironment while minimizing systemic dissemination are needed to realize the potential of cytokine-based immunotherapies. Recently, co-formulations of cytokines with chitosan solutions hav...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Chemistry, Pharmaceutical
Share to Chitosan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dose-Response Relationship, Drug

Share to Drug Delivery Systems

Share to Injections

Share to Interleukin-12

Share to Leukocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 23453060
DOI: 10.1016/j.biomaterials.2013.02.031
PMCID: PMC3613143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23453060-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Role of chitosan co-formulation in enhancing interleukin-12 delivery and antitumor activity.PMID 23453060Read ↗

<i>In situ</i> administration of cytokine combinations induces tumor regressionSemantic proximity Read ↗

Spatially Tuned Localization of Interleukins and OX40 Agonists Enhances Synergistic Anti-Tumor ImmunitySemantic proximity Read ↗

Chitosan thermogels for local expansion and delivery of tumor-specific T lymphocytes towards enhanced cancer immunotherapies.Semantic proximity Read ↗

Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses.Semantic proximity Read ↗

Intratumoral injection of interleukin-12 plasmid DNA, either naked or in complex with cationic lipid, results in similar tumor regression in a murine model.Semantic proximity Read ↗

Local and systemic activity of the polysaccharide chitosan at lymphoid tissues after oral administration.Semantic proximity Read ↗

Gene Therapy of Cancer Based on Interleukin 12Semantic proximity Read ↗

Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery SystemsSemantic proximity Read ↗

Superior protective and therapeutic effects of IL-12 and IL-18 gene-transduced dendritic neuroblastoma fusion cells on liver metastasis of murine neuroblastoma.Semantic proximity Read ↗

Immunohistochemical characterisation of immunological changes at the tumour site after chemo-immunotherapy with doxorubicin, interleukin-2 and interferon-gamma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.