Article

Variable Retention of Differentiation-specific DNA Replication Timing in Human Pediatric Leukemia

2019-02-13

Abstract excerpt

<h4>ABSTRACT</h4> Human B-lineage precursor acute lymphoid leukemias (BCP-ALLs) comprise a group of genetically and clinically distinct disease entities with features of differentiation arrest at known stages of normal B-lineage differentiation. We previously showed BCP-ALL cells display unique and clonally heritable DNA-replication timing (RT) programs; i.e., programs describing the variable order of replication...

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Literature Corpus work: 38065f0a-008b-57f2-b153-1fce6fa50fc8
DOI: 10.1101/549196

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