Article

The USTC complex co-opts an ancient machinery to drive piRNA transcription in <i>C. elegans</i>

2018-07-25

Abstract excerpt

<h4>ABSTRACT</h4> Piwi-interacting RNAs (piRNAs) engage Piwi proteins to suppress transposons and non-self nucleic acids, maintain genome integrity, and are essential for fertility in a variety of organisms. In C. elegans most piRNA precursors are transcribed from two genomic clusters that contain thousands of individual piRNA transcription units. While a few genes have been shown to be required for piRNA biogen...

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Literature Corpus work: 3f233361-1677-5cc1-b258-5554a7ec66e8
DOI: 10.1101/377390

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