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Article

Genome Wide Epistasis Study of On-Statin Cardiovascular Events with Iterative Feature Reduction and Selection

2020-04-03

Abstract excerpt

<h4>Background</h4> Predicting risk for major adverse cardiovascular events (MACE) is an evidence-based practice that incorporates lifestyle, history, and other risk factors. Statins reduce risk for MACE by decreasing lipids, but it is difficult to stratify risk following initiation of a statin. Genetic risk determinants for on-statin MACE are low-effect size and impossible to generalize. Our objective was to dete...

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Literature Corpus work
37877803-a29e-5e52-a686-050b3f419631
DOI
10.1101/2020.03.31.20044255
Open publication

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Genome Wide Epistasis Study of On-Statin Cardiovascular Events with Iterative Feature Reduction and SelectionDOI 10.1101/2020.03.31.20044255
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