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Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelae

2023-07-25

Abstract excerpt

<h4>Aims</h4> The study aimed to discover novel genetic loci for atrial fibrillation (AF), explore the shared genetic etiologies between AF and other cardiovascular and cardiometabolic traits, and uncover AF pathogenesis using Mendelian randomization analysis. <h4>Methods and results</h4> We conducted a genome-wide association study meta-analysis including 109,787 AF cases and 1,165,920 controls of European ancest...

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Literature Corpus work
9410f2d5-b6cd-5741-8bc7-e0c5bcfe0fcf
DOI
10.1101/2023.07.20.23292938
Open publication

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Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelaeDOI 10.1101/2023.07.20.23292938
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