Article

Screening human embryos for polygenic traits has limited utility

2019-05-05

Abstract excerpt

Genome-wide association studies have led to the development of polygenic score (PS) predictors that explain increasing proportions of the variance in human complex traits. In parallel, progress in preimplantation genetic testing now allows genome-wide genotyping of embryos generated via in vitro fertilization (IVF). Jointly, these developments suggest the possibility of screening embryos for polygenic traits such...

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Literature Corpus work: 3768055a-6a4c-55ac-b533-eb282ffdfa12
DOI: 10.1101/626846

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