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Article

From Genotype to Phenotype: Polygenic Prediction of Complex Human Traits.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

Raben Timothy G, Lello Louis, Widen Erik, Hsu Stephen D H

Abstract excerpt

Decoding the genome confers the capability to predict characteristics of the organism (phenotype) from DNA (genotype). We describe the present status and future prospects of genomic prediction of complex traits in humans. Some highly heritable complex phenotypes such as height and other quantitative traits can already be predicted with reasonable accuracy from DNA alone. For many diseases, including important...

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PMID: 35451785
DOI: 10.1007/978-1-0716-2205-6_15

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