Article

KRAB Zinc Finger Proteins coordinate across evolutionary time scales to battle retroelements

2018-09-27

Abstract excerpt

KRAB Zinc Finger Proteins (KZNFs) are the largest and fastest evolving family of human transcription factors 1,2 . The evolution of this protein family is closely linked to the tempo of retrotransposable element (RTE) invasions, with specific KZNF family members demonstrated to transcriptionally repress specific families of RTEs 3,4 . The competing selective pressures between RTEs and the KZNFs results in evolut...

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Literature Corpus work: 373c2059-48cc-50e0-9979-4478b6c4f012
DOI: 10.1101/429563

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