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Article

Rapid sequence and expression divergence suggest selection for novel function in primate-specific KRAB-ZNF genes.

Molecular biology and evolution - 1 Nov 2010

Nowick Katja, Hamilton Aaron T, Zhang Huimin, Stubbs Lisa

Abstract excerpt

Recent segmental duplications (SDs), arising from duplication events that occurred within the past 35-40 My, have provided a major resource for the evolution of proteins with primate-specific functions. KRAB zinc finger (KRAB-ZNF) transcription factor genes are overrepresented among genes contained within these recent human SDs. Here, we examine the structural and functional diversity of the 70 human KRAB-ZNF...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20573777
DOI: 10.1093/molbev/msq157
PMCID: PMC2981486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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