Article

Automatic generation of ground truth data for the evaluation of clonal grouping methods in B-cell populations

2020-12-01

Abstract excerpt

<h4>Motivation</h4> The adaptive B-cell response is driven by the expansion, somatic hypermutation, and selection of B-cell clones. Their number, size and sequence diversity are essential characteristics of B-cell populations. Identifying clones in B-cell populations is central to several repertoire studies such as statistical analysis, repertoire comparisons, and clonal tracking. Several clonal grouping methods...

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Literature Corpus work: 37371dfb-4c20-5539-b904-2df23b9928b2
DOI: 10.1101/2020.11.30.404046

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