Article

A multi-objective based clustering for inferring BCR clones from high-throughput B cell repertoire data

2021-10-01

Abstract excerpt

The adaptive B cell response is driven by the expansion, somatic hypermutation, and selection of B cell clones. A high number of clones in a B cell population indicates a highly diverse repertoire, while clonal size distribution and sequence diversity within clones can be related to antigen’s selective pressure. Identifying clones is fundamental to many repertoire studies, including repertoire comparisons, clonal...

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Literature Corpus work: c056f092-02aa-52c6-9840-672e2ce19fe6
DOI: 10.1101/2021.10.01.462736

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