Article

A haplotype-aware de novo assembly of related individuals using pedigree graph

2019-03-17

Abstract excerpt

<h4>Motivation</h4> Reconstructing high-quality haplotype-resolved assemblies for related individuals of various species has important applications in understanding Mendelian diseases along with evolutionary and comparative genomics. Through major genomics sequencing efforts such as the Personal Genome Project, the Vertebrate Genome Project (VGP), the Earth Biogenome Project (EBP) and the Genome in a Bottle proje...

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Literature Corpus work: 36dcf6ae-3ac9-590f-a60f-06b95f435e34
DOI: 10.1101/580159

Open publication

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