Article

Identification of meiotic recombination through gamete genome reconstruction using whole genome linked-reads

2018-07-06

Abstract excerpt

Meiotic recombination (MR), which transmits exchanged genetic materials between homologous chromosomes to offspring, plays a crucial role in shaping genomic diversity in eukaryotic organisms. In humans, thousands of meiotic recombination hotspots have been mapped by population genetics approaches. However, direct identification of MR events for individuals is still challenging due to the difficulty in resolving th...

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Literature Corpus work: e9b71ae3-7597-5cb0-8b6d-7f50b67c2ab5
DOI: 10.1101/363341

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