Article
De novo phasing resolves haplotype sequences in complex plant genomes.
Plant biotechnology journal - 1 Jun 2022
Guk Ji-Yoon, Jang Min-Jeong, Choi Jin-Wook, Lee Yeon Mi, Kim Seungill
Abstract excerpt
Genome phasing is a recently developed assembly method that separates heterozygous eukaryotic genomic regions and builds haplotype-resolved assemblies. Because differences between haplotypes are ignored in most published de novo genomes, assemblies are available as consensus genomes consisting of haplotype mixtures, thus increasing the need for genome phasing. Here, we review the operating principles and...
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