Article

Haplotype-Resolved Assembly for Synthetic Long Reads Using a Trio-Binning Strategy

2020-06-02

Abstract excerpt

<h4>ABSTRACT</h4> The accuracy and completeness of genome haplotyping are crucial for characterizing the relationship between human disease susceptibility and genetic variations, especially for the heterozygous variations. However, most of current variations are unphased genotypes, and the construction of long-range haplotypes remains challenging. We introduced a de novo haplotype-resolved assembly tool, HAST th...

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Literature Corpus work: 21a76212-bc23-5540-a888-47f96c664a19
DOI: 10.1101/2020.06.01.126995

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