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Article

gcaPDA: a haplotype-resolved diploid assembler.

BMC bioinformatics - 14 Feb 2022

Xie Min, Yang Linfeng, Jiang Chenglin, Wu Shenshen, Luo Cheng, Yang Xin, He Lijuan, Chen Shixuan, Deng Tianquan, Ye Mingzhi, Yan Jianbing, Yang Ning

Abstract excerpt

BACKGROUND: Generating chromosome-scale haplotype resolved assembly is important for functional studies. However, current de novo assemblers are either haploid assemblers that discard allelic information, or diploid assemblers that can only tackle genomes of low complexity. RESULTS: Here, Using robust programs, we build a diploid genome assembly pipeline called gcaPDA (gamete cells assisted Phased Diploid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35164674
DOI: 10.1186/s12859-022-04591-4
PMCID: PMC8842951

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