Article

FM-GPT: Bayesian fine mapping for phenome-wide transcriptome-wide association studies

2026-04-11

Abstract excerpt

Transcriptome-wide association studies (TWAS) integrate genome wide association studies with expression quantitative trait locus reference panels to identify genes associated with traits of interest. However, linkage disequilibrium and correlated gene expression can induce spurious TWAS signals, motivating fine mapping methods to prioritize putatively causal genes within associated loci. The rapid growth of large-...

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Literature Corpus work: 36bba3f2-84cb-5bc3-880f-5aa913041127
DOI: 10.64898/2026.04.07.717122

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