Article

Genome-wide fine-mapping improves identification of causal variants

2024-08-07

Abstract excerpt

<title>Abstract</title> <p>Fine-mapping refines genotype-phenotype association signals to identify causal variants underlying complex traits. However, current methods typically focus on individual genomic segments without considering the global genetic architecture. Here, we demonstrate the advantages of performing genome-wide fine-mapping (GWFM) and develop methods to facilitate GWFM. In simulations and real dat...

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Literature Corpus work: f615fc48-a6fc-5a86-a232-088059a19919
DOI: 10.21203/rs.3.rs-4759390/v1

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