FABIO: TWAS fine-mapping to prioritize causal genes for binary traits.

Abstract excerpt

Transcriptome-wide association studies (TWAS) have emerged as a powerful tool for identifying gene-trait associations by integrating gene expression mapping studies with genome-wide association studies (GWAS). While most existing TWAS approaches focus on marginal analyses through examining one gene at a time, recent developments in TWAS fine-mapping methods enable the joint modeling of multiple genes to refine...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Asthma
• Share to Chromosome Mapping
• Share to GATA3 Transcription Factor