Article

Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy

2022-03-20

Abstract excerpt

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to pose serious threats to global health. We previously reported that AAK1, BIKE and GAK, members of the Numb-associated kinase family, control intracellular trafficking of multiple RNA viruses during viral entry and assembly/egress. Here, using both genetic and pharmacological appr...

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Identifiers and source

Literature Corpus work: 3687d221-e367-52e1-ae1e-ab65b3226668
DOI: 10.1101/2022.03.18.484178

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