Article

The FDA-approved drug Alectinib compromises SARS-CoV-2 nucleocapsid phosphorylation and inhibits viral infection in vitro

2020-08-14

Abstract excerpt

<h4>ABSTRACT</h4> While vaccines are vital for preventing COVID-19 infections, it is critical to develop new therapies to treat patients who become infected. Pharmacological targeting of a host factor required for viral replication can suppress viral spread with a low probability of viral mutation leading to resistance. In particular, host kinases are highly druggable targets and a number of conserved coronavirus...

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Literature Corpus work: a58f4ccb-4a2a-5888-aac0-3e623f05a52a
DOI: 10.1101/2020.08.14.251207

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