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Host cell potassium ion channels KCNJ2 (K <sub>IR</sub> 2.1), KCNJ13 (K <sub>IR</sub> 7.1) and KCNMA1 (BK <sub>Ca</sub> ) mediate escape of Bunyamwera virus from late endosomal compartments

2026-01-12

Abstract excerpt

The Orthobunyavirus genus within the Peribunyaviridae family of enveloped arthropod-borne negative-sense RNA viruses includes species associated with serious or fatal disease in both animals and humans such as Schmallenberg, La Crosse and Oropouche viruses. Orthobunyaviruses (OBVs) are internalised into cells by endocytosis and release their genomes following fusion with late endosomal (LE) membranes, triggered...

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Literature Corpus work
6fed2c44-4881-5c35-90de-681ed9ae8d18
DOI
10.64898/2026.01.12.698685
Open publication

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Host cell potassium ion channels KCNJ2 (K <sub>IR</sub> 2.1), KCNJ13 (K <sub>IR</sub> 7.1) and KCNMA1 (BK <sub>Ca</sub> ) mediate escape of Bunyamwera virus from late endosomal compartmentsDOI 10.64898/2026.01.12.698685
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