Article

Leucine-rich Repeat Protein LRRC37A Acts as a Molecular Scaffold Coordinating IAM-PT-NE Complex Assembly and Sperm Head Morphogenesis

2026-08-14

Abstract excerpt

<title>Abstract</title> Sperm head morphogenesis relies on tight structural coordination between the acrosome, perinuclear theca (PT) and nuclear envelope (NE), but the mechanisms governing this ternary complex remain poorly defined. Here, we demonstrate that testis-specific protein LRRC37A is essential for maintaining sperm head integrity and male fertility. Male <italic>Lrrc37a</italic> knockout ( <ital...

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Literature Corpus work: 368122d5-e9a7-5d83-985b-a89592466bea
DOI: 10.21203/rs.3.rs-10531477/v1

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Leucine-rich Repeat Protein LRRC37A Acts as a Molecular Scaffold Coordinating IAM-PT-NE Complex Assembly and Sperm Head MorphogenesisDOI 10.21203/rs.3.rs-10531477/v1Read

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