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Novel Nuclear Roles for Testis-Specific ACTL7A and ACTL7B Supported by <i>In Vivo</i> Characterizations and AI Facilitated <i>In Silico</i> Mechanistic Modeling with Implications for Epigenetic Regulation in Spermiogenesis

2024-02-29

Abstract excerpt

A mechanistic role for nuclear function of testis-specific actin related proteins (ARPs) is proposed here through contributions of ARP subunit swapping in canonical chromatin regulatory complexes. This is significant to our understanding of both mechanisms controlling regulation of spermiogenesis, and the expanding functional roles of the ARPs in cell biology. Among these roles, actins and ARPs are pivotal not onl...

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Literature Corpus work
53a91f17-8526-56f5-8db3-227cc92ab923
DOI
10.1101/2024.02.29.582797
Open publication

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Novel Nuclear Roles for Testis-Specific ACTL7A and ACTL7B Supported by <i>In Vivo</i> Characterizations and AI Facilitated <i>In Silico</i> Mechanistic Modeling with Implications for Epigenetic Regulation in SpermiogenesisDOI 10.1101/2024.02.29.582797
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