Article
KATP channels as molecular sensors of cellular metabolism.
Nature - 23 Mar 2006
Nichols Colin G
Abstract excerpt
In responding to cytoplasmic nucleotide levels, ATP-sensitive potassium (K(ATP)) channel activity provides a unique link between cellular energetics and electrical excitability. Over the past ten years, a steady drumbeat of crystallographic and electrophysiological studies has led to detailed structural and kinetic models that define the molecular basis of channel activity. In parallel, the uncovering of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
