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Article

Influence of inositol pyrophosphates on cellular energy dynamics.

Science (New York, N.Y.) - 11 Nov 2011

Szijgyarto Zsolt, Garedew Assegid, Azevedo Cristina, Saiardi Adolfo

Abstract excerpt

With its high-energy phosphate bonds, adenosine triphosphate (ATP) is the main intracellular energy carrier. It also functions in most signaling pathways, as a phosphate donor or a precursor for cyclic adenosine monophosphate. We show here that inositol pyrophosphates participate in the control of intracellular ATP concentration. Yeasts devoid of inositol pyrophosphates have dysfunctional mitochondria but,...

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Identifiers

PMID: 22076377
DOI: 10.1126/science.1211908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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