Article

Resolvin E1 improves efferocytosis and rescues severe aplastic anemia in mice

2023-02-15

Abstract excerpt

Current treatments for severe aplastic anemia (SAA) rely on hematopoietic stem cell (HSC) transplantation and immunosuppressive therapies, however these treatments are not always effective. While immune-mediated destruction and inflammation are known drivers of SAA, the underlying mechanisms that lead to persistent inflammation are unknown. Using an established mouse model of SAA, we observed a significant increas...

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Literature Corpus work: 364b3ab0-7181-5a62-8d3b-ae35108213c4
DOI: 10.1101/2023.02.15.528688

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