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Erythrophagocytes in hemolytic anemia, wound healing, and cancer

10 Sept 2022

Abstract excerpt

Hemolysis is a ubiquitous pathology defined as premature red blood cell destruction within the circulation or local tissues. One of the most archetypal functions of macrophages is phagocytosis of damaged or extravasated red blood cells, preventing the extracellular release of toxic hemoglobin and heme. Upon erythrophagocytosis, spiking intracellular heme concentrations drive macrophage transformation into...

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Share to Erythrocyte Function and Pathophysiology
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PMID: 36096988
DOI: 10.1016/j.molmed.2022.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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