Article

CDK9 regulates neointima formation following vascular injury via targeting transcription factor Twist1

2026-01-07

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Restenosis is a major limiting factor of percutaneous coronary intervention (PCI), accompanied by abnormal proliferation, migration and phenotypic switching of vascular smooth muscle cells (VSMCs). As a key component of positive transcription factor-b (P-TEFb), CDK9 phosphorylates RNA polymerase II and regulates various genes that are involved in the regulatio...

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Literature Corpus work: 361f3e04-e872-5510-a19c-d9fe5bb8cbba
DOI: 10.21203/rs.3.rs-8452448/v1

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