Article
Role of Krüppel-like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells.
IUBMB life - 1 Feb 2010
Zheng Bin, Han Mei, Wen Jin-Kun
Abstract excerpt
Phenotypic switching and proliferation of vascular smooth muscle cells (VSMCs) are critical components in the development of many vascular proliferation diseases such as atherosclerosis and restenosis after percutaneous coronary interventions. Krüppel-like factor 4 (KLF4) has been shown to play a key role in VSMC proliferation and differentiation. The focus of this review is to provide an overview for...
Topics
- Animals
- Cell Differentiation
- Cell Proliferation
- Humans
- Kruppel-Like Factor 4
- Kruppel-Like Transcription Factors
- Muscle, Smooth, Vascular
- Phenotype