Article

A computational HLA allele-typing protocol to de-noise and leverage nanopore amplicon data

2024-02-29

Abstract excerpt

<title>Abstract</title> <p> <underline> <bold>Background:</bold> </underline> Rapid turnaround time for a high-resolution deceased donor human leukocyte antigen (HLA) typing is critical to improve organ transplantation outcomes. Third generation DNA sequencing platforms such as Oxford Nanopore (ONT) offer the opportunity to deliver rapid results at single nucleotide level resolution, in particular sequencing...

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Literature Corpus work: 361d9d8f-813f-56c1-a708-335a4b52ef3e
DOI: 10.21203/rs.3.rs-3937898/v2

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