Article
High resolution HLA genotyping with third generation sequencing technology-A multicentre study.
HLA - 1 Aug 2024
Buhler Stéphane, Nørgaard Maja, Steffensen Rudi, Kløve-Mogensen Kirstine, Møller Bjarne Kuno, Grossmann Rebecca, Ferrari-Lacraz Sylvie, Lehmann Claudia
Abstract excerpt
Molecular HLA typing techniques are currently undergoing a rapid evolution. While real-time PCR is established as the standard method in tissue typing laboratories regarding allocation of solid organs, next generation sequencing (NGS) for high-resolution HLA typing is becoming indispensable but is not yet suitable for deceased donors. By contrast, high-resolution typing is essential for stem cell transplantation...
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