Article
HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy.
Proceedings of the National Academy of Sciences of the United States of America - 30 Mar 1999
Jeffery K J, Usuku K, Hall S E, Matsumoto W, Taylor G P, Procter J, Bunce M, Ogg G S, Welsh K I, Weber J N, Lloyd A L, Nowak M A, Nagai M, Kodama D, Izumo S, Osame M, Bangham C R
Abstract excerpt
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load. However, it is not known whether a persistent class I HLA-restricted antiviral cytotoxic T lymphocyte (CTL) respons...
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