Article
HLA class I alleles in HTLV-1-associated myelopathy and asymptomatic carriers from the Brazilian cohort GIPH.
Medical microbiology and immunology - 1 Feb 2009
Catalan-Soares B C, Carneiro-Proietti Anna Bárbara F, Da Fonseca F G, Correa-Oliveira R, Peralva-Lima D, Portela R, Ribas J G, Gonçalves D U, Proietti F A
Abstract excerpt
INTRODUCTION AND OBJECTIVES: The development of HTLV-1-associated myelopathy (HAM/TSP) in HTLV-1-infected individuals is probably a multi-factor event, in which the immune system plays a crucial role. The efficiency of the host immunity seems to be one of the in vivo determining factors of the proviral load levels and is regulated by genes associated with MHC class I alleles (HLA). Protection or predisposition to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
