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Article

The FAS-670 AA genotype is associated with high proviral load in peruvian HAM/TSP patients.

Journal of medical virology - 1 Apr 2017

Rosado Jason, Morales Sandra, López Giovanni, Clark Daniel, Verdonck Kristien, Gotuzzo Eduardo, Van Camp Guy, Talledo Michael

Abstract excerpt

Human T-lymphotropic virus 1 (HTLV-1) is the etiologic agent of the HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Apoptosis is a mechanism of defense elicited by many triggers, including cross-linking of the FAS receptor expressed in viruses-infected cells, and the ligand FASL presented by T-cytotoxic cells. As HAM/TSP has been associated with high levels of proviral load (PVL), we...

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Identifiers

PMID: 27603042
DOI: 10.1002/jmv.24681

Genes

FAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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