Article

Targeted and selective knockout of the TLQP-21 neuropeptide unmasks its unique role in energy homeostasis

2023-03-23

Abstract excerpt

Pro-peptide precursors are processed into biologically active peptide hormones or neurotransmitters, each playing an essential role in physiology and disease. Genetic loss of function of a pro-peptide precursor results in the simultaneous ablation of all biologically-active peptides within that precursor, often leading to a composite phenotype that can be difficult to align with the loss of specific peptide compon...

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Literature Corpus work: 35bcb999-2e10-51b0-b77f-19d1d9909529
DOI: 10.1101/2023.03.23.532619

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