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Article

A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.

PloS one - 1 Jan 2015

Mang Géraldine M, Pradervand Sylvain, Du Ngoc-Hien, Arpat Alaaddin Bulak, Preitner Frédéric, Wigger Leonore, Gatfield David, Franken Paul

Abstract excerpt

MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid metabolism. We used a neuronal-specific inhibition of miRNA mat...

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PMID: 25629159
DOI: 10.1371/journal.pone.0116760
PMCID: PMC4309537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25629159-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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