The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure.

doi:10.1096/fj.13-239509

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Article

The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2014

Fargali Samira, Garcia Angelo L, Sadahiro Masato, Jiang Cheng, Janssen William G, Lin Wei-Jye, Cogliani Valeria, Elste Alice, Mortillo Steven, Cero Cheryl, Veitenheimer Britta, Graiani Gallia, Pasinetti Giulio M, Mahata Sushil K, Osborn John W, Huntley George W, Phillips Greg R, Benson Deanna L, Bartolomucci Alessandro, Salton Stephen R

Abstract excerpt

Secretion of proteins and neurotransmitters from large dense core vesicles (LDCVs) is a highly regulated process. Adrenal LDCV formation involves the granin proteins chromogranin A (CgA) and chromogranin B (CgB); CgA- and CgB-derived peptides regulate catecholamine levels and blood pressure. We investigated function of the granin VGF (nonacronymic) in LDCV formation and the regulation of catecholamine levels and...

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PMID: 24497580
DOI: 10.1096/fj.13-239509
PMCID: PMC3986843

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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