Article

Chromatin dynamics during hematopoiesis reveal discrete regulatory modules instructing differentiation

2020-04-03

Abstract excerpt

Lineage commitment and differentiation is driven by the concerted action of master transcriptional regulators at their target chromatin sites. Multiple efforts have characterized the key transcription factors (TFs) that determine the various hematopoietic lineages. However, the temporal interactions between individual TFs and their chromatin targets during differentiation and how these interactions dictate lineage...

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Identifiers and source

Literature Corpus work: 35942f2b-ff41-553b-9226-f62ac2800b33
DOI: 10.1101/2020.04.02.022566

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